In theory, as you probably know, setting the balance screw should just be adjusting it so that the slack between the 2 carbs is just removed, so that when you open the throttle the carbs move from idle to fast idle at the same time. What is happening that makes you think that the balance screw is not in the correct place? Does it 'stumble' or not rev cleanly when you open the throttle? Are you sure that there is nothing else amiss with the engine? ( ie intake vacuum leaks, carb air leaks, sticky carb pistons, tappets not set, ignition problems,old air filter) I know from experience that balancing SU carbs when some other part of the engine is not quite right is almost impossible. I can't tell how bad your car runs from the info you have posted, but I would say that if it runs well with good colour spark plugs and revs cleanly from idle you are 95% of the way to having the best possible settings.
Let us know how thing go